Product information®

Sterile Solution based on hyaluronic acid for intravesical irrigation. INSTYLAN is intended for irrigation into bladder cavity that provides the formation of a viscous elastic film on the surface of mucous layer. The irrigation provides temporary protection and restoration of bladder mucous layer during various surgeries, inflammation of the mucous layer of the bladder, radiation therapy.

Indications for use®

INSTYLAN is intended for irrigation into bladder cavity that provides the formation of a viscous elastic film on the surface of mucous layer to:
-protecting it from external effects during various surgeries (ureteroscopy, cystoscopy, transurethral resection of adenoma and radiation therapy oflesser pelvis organs, etc)
-protect it from the harmful impact of bladder content (urina) in case of injury or from inflammation of the mucous layer of the bladder, like cystitis.
INSTYLAN is intended for irrigation of the bladder when using a urological catheter. The irrigation provides temporary protection and restoration of bladder mucous layer during various surgeries (urethra cystoscopy, radiation therapy, etc).

Mechanism of action

Hyaluronic acid plays a key role in restoring the GAG layer and produces its e ect in the submucosa, exactly where the process of epithelial regeneration initiates.

How to use

Irrigation into the bladder should be provided by a trained medical specialist in specialized premise with appropriate equipment and aseptic conditions.

Publication

Intravesical hyaluronic acid instillation

Intravesical instillation of hyaluronic acid repairs the GAG layer on the urothelial surface and prevents therefore bacterial adhesion. EAU Guidelines show that endovesical instillations of hyaluronic acid and chondroitin sulphate have been used for glycosaminoglycan (GAG) layer replenishment in the treatment of interstitial cystitis, overactive bladder, radiation cystitis, and for prevention of rUTI.

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SELF-MEDICATION CAN BE HARMFUL TO YOUR HEALTH

Before using the product offered on this information resource, it is recommended to consult your doctor and read the instructions.

Information about medical products for the professional work of health professionals. INSTYLAN (INSTILAN) 0.16% colorless, transparent, viscous gel of hyaluronic acid of non-animal origin, sterile, physiological pH.

INSTYLAN 0,16% approved as Class ІІa medical devices. EU Declaration of Conformity. Registration number: DD 60107286 0001 Manufacturer: Diaco Biofarmaceutici S.R.L. Via Flavia 124, 34147, Trieste, Italy. E-mail: info@diaco.it. www.diaco.it.

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